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Bioscience Reports, May 2021, ePublication 3

Difference Between Normal Reactions and Serious Complications A normal tirzepatide injection site reaction typically appears within a few minutes to hours after injection and resolves within 24-48 hours

The expression of CD14 + ( Figure 7B ) increased by 47% from one d ap to 4 h pp , persisted on this higher level until 72 h pp and decreased again at d 7 pp to the initial level until the end of the trial