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Acknowledgments We thank the UK Biobank study, and the summary statistics data of UKB can be download from Neale lab ( and other GWAS summary-level data, which have been downloaded from We also thank all the reviewers and editors for their useful suggestions for improving this study

Leukocytosis, thrombocytosis, eosinophilia, anemia, macrocytosis, or an abnormal blood smear all raise the priority of a hematologic cause

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