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The mobile phase system consisted of two phases, phase A (water) and phase B (water/acetonitrile, 1:9, v/v), and 10 mM of ammonium acetate was added to both of the phases

Early studies suggested that carnitine supplementation at 24 g/d could directly lower the respiratory quotient, thereby prolonging exercise time and increasing critical exercise intensity, with a recommended dose of 2 g/d

The human body uses acetyl l-carnitine to breakdown fatty acid to create energy by transporting fatty acids across the mitochondria membrane

Other works, however, have shown that naltrexone pre-treatment did not affect the antidepressant activities of KET in depressed individuals (Marton et al., 2019