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It was developed by Russian researchers as a novel anxiolytic compound designed to deliver calming, mood-stabilizing benefits without the drawbacks commonly associated with traditional benzodiazepines such as drowsiness, cognitive dulling, or dependency

Supplementing with 1540 mg of RiaGev dosed twice daily for five days significantly increased NAD+ in the blood 11% over baseline as well as over placebo

This process would explain the delineation between lesional and non-lesional KP skin, while also explaining some of the variance seen in KP subtypes