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Finally, we address critical translational challenges, specifically the need to establish long-term reproductive and offspring safety, providing a roadmap for developing true disease-modifying treatments for PCOS

8,13 Estrogens and progestins lower LH levels, inhibiting androgen production in the ovaries, and increase levels of SHBG, reducing androgen activity

Curcumin ameliorates hepatic steatosis by improving intestinal barrier integrity and decreasing lipopolysaccharide (LPS)-mediated hepatic inflammation

1-Palmitoyl-2-(13-hydroxy-cis-9,trans-11-octadecadienoyl)-L-3-phosphatidylcholine 1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC is an oxidized phospholipid that contains palmitic acid and 13(S)-HODE at the sn-1 and sn-2 positions, respectively