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Fibrinogen was identified as a major oxidized protein in plasma

Article reviewed by: Dr

The plausible main reason for -cell protective effects of GSH differing from other antioxidant effects is that GSH has multiple functions, such as maintaining levels of reduced glutaredoxin and glutathione peroxidase 35 and maintaining exogenous antioxidants such as vitamins C and E in their reduced (active) forms 36,37,38

Prologue This review re-examines the under-appreciated molecular manifestation of Friedreichs ataxia (FRDA) associated with oxidative modification of the cytoskeleton