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Therefore, while PDOs serve as an invaluable tool for understanding the intrinsic properties of chemoresistant tumor cells, they cannot fully capture the extrinsic factors that contribute to resistance

The peptide showed no impact on blood pressure, heart rate, or laboratory parameters across extensive testing

the invention provides methods of reversing, ameliorating or slowing progression of at least one symptom of Lewy body pathology in a patient in need thereof

This study design, animal selection, handling, and treatment were all in accordance with ARRIVE and Animal Care guidelines (Palladin Institute of Biochemistry of the NASU Animal Care and Use Committee protocol #1 dated Jan 10 2022)