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Similarly, the key molecular events that cause changes in the generation of ROS in PC and the role for therapeutic strategies aimed at ameliorating oxidative stress need to be identified

C., Ochoa, A

Splenectomized 4.2 / mice treated with mitapivat had significant reductions in Vcam1, Icam1, and Tbx expression in isolated aorta compared with splenectomized 4.2 / mice (Figure 6F and Supplemental Figure 10C)