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The full effect may take 8 weeks or longer

10.1016/j.freeradbiomed.2018.09.043 33 HolohanC.Van SchaeybroeckS.LongleyD

Clinical trials, including research in diabetic hyperlipidemic patients on dialysis, have reported meaningful reductions in total cholesterol, very-low-density lipoprotein cholesterol (VLDL-C), and triglycerides at doses around 900 mg per day