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The complement system: A powerful modulator and effector of astrocyte function in the healthy and diseased central nervous system

However, while the G12D, G12V and G12C direct 13 C-glucose carbon flux towards glutamine synthesis, the G12A mutant maintains a higher flux through the TCA cycle and high glutamate levels

[92] suggested that the activation of brain areas that control emotional motivation, balance of emotions, and autonomic responses to pain in IBS-C patients differed from that in patients with the other IBS subtypes

When BCAT 2 is knocked down, depletion of BCKAs and its derivative acetyl-CoA promotes WAT brown steatosis and energy expenditure