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Protective effect of edaravone against A25-35-induced mitochondrial oxidative damage in sh-sy5y cells

Debuf, Y

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The passage through the outer mitochondrial membrane occurs by free diffusion through non-specific voltage-dependent anion channels (VDACs) or porins, the most abundant proteins of the outer mitochondrial membrane, whose function is to mediate the exchange of ions and small molecules, including, in addition to pyruvate, also ATP, NADH and others, between the cytosol and the intermembrane space of mitochondria