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Indeed, cancer progression is marked by characteristics such as sustained proliferative signaling, evasion of growth suppressors, resistance to apoptosis, angiogenesis, and metastasis, as well as inflammation and genomic instability (Hanahan and Weinberg 2017)

Pharmacogenomics The response to any particular drug is influenced by drug's kinetic properties (pharmacokinetics) and its effects (pharmacodynamics) An individual's response to a drug can be influenced by genes that code for drug-metabolizing enzymes, receptors and transporters

This software was developed by the Federal University of So Carlos (UFSCar) and is available for download ( The review followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines (Page et al., 2021) and was conducted in three stages: planning, execution, and summarization