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(PubMed) Choudhury A, Jena A, Jearth V, et al

The current NICE guidance on B12 and folate deficiency sets this out clearly

Second, an in vitro chromosome aberration assay was performed in Chinese Hamster Ovary (CHO) cells treated with AOD9604 (20, 50, 100, 200 g/mL) in the absence or presence of an S-9 metabolic activation system