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Although the pathophysiology of this disease remains unclear, there are several explanatory hypotheses, including direct toxicity of excess metabolites (methylmalonic acid and homocysteine), enhanced oxidative stress and mitochondrial disorders ( For combined MMA patients, extra mechanisms relating homocysteine may be involved

Indeed, excess sebum is one of the key factors in this condition, as it promotes the obstruction of pilosebaceous follicles and the proliferation of Cutibacterium acnes , a bacterium involved in the development of inflammatory lesions

Peptidomimetic targeting of critical androgen receptor-coregulator interactions in prostate cancer

It is also gluten-free, making it ideal for those on a gluten-free diet or with food sensitivities