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Description

The p17 nonstructural protein of avian reovirus triggers autophagy enhancing virus replication via activation of phosphatase and tensin deleted on chromosome 10 (PTEN) and AMP-activated protein kinase (AMPK), as well as dsRNA-dependent protein kinase (PKR)/eIF2 signaling pathways

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In particular, standard 1D proton spectra and 2D experiments (clean total-correlation spectroscopy (TOCSY) and heteronuclear single quantum coherence (HSQC)) were acquired providing one-dimensional metabolic profiles and homonuclear and heteronuclear spectra for metabolite identification