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Group 2 was diabetic untreated (DU)

doi: 10.1002/ijc.28149 25 TibulloDGiallongoCRomanoAVicarioNBarbatoAPuglisiFet al

MDSCs play a pivotal role in maintaining immune tolerance and preventing excessive immune responses (82)

The intended final sample size was 60 patients (20 per site) for each Phase Group, and 30 healthy controls (10 per site) age matched to each of the patient groups giving a planned total sample of 180