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Cell Metabolism , [online] 22(1), pp.6576

Determining the ability of the test compound to bind to the NOVX protein can be accomplished, for example, by coupling the test compound with a radioisotope or enzymatic label such that binding of the test compound to the NOVX protein or biologically-active portion thereof can be determined by detecting the labeled compound in a complex

The Cd selectivity of this protein and the rapid up-regulation of its gene upon Cd exposure suggest that its Cd-specific function is dedicated to detoxifying this metal, with an important contribution from digestive gland cells (Vega et al