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Accordingly, drug-mediated regulation of Wnt/-catenin signalling activity to induce liver regeneration would benefit this group of patients based on the key role of Wnt/-catenin signalling in the pathobiology of non-tumour diseases such as steatohepatitis, 78,310 cholestasis, 311 and liver fibrosis

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In chemical synthesis, Se in the +4 valence state (e.g., selenite, selenite, or SeO 2 ) is commonly used as a precursor, while reducing agents (e.g., ascorbic acid and glutathione [GSH]) and stabilizers (e.g., chitosan and pectin) are used for the formation and maintenance of SeNPs (244, 245)

Oxid Med Cell Longev 2021(1):6640206 Madkour LH (2019) Function of reactive oxygen species (ROS) inside the living organisms and sources of oxidants