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87 Studies have also shown that hypoxia promotes the development of ferroptosis by activating HIFs, which induce the increased expression of lipid-related proteins and drive the enrichment of polyunsaturated lipids to induce ferroptosis

As described above, eosinophil-deficient mice (dblGATA mice) have been shown to exhibit delayed recovery from acute colitis in some studies, possibly due to the loss of eosinophil-derived healing factors, which may include ROS and ROS-induced signals (though results vary across models)

Protein-bound molecules: a large family with a bad character