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The heightened incidence of OSA in the presence of obesity and asthma is concomitant with an escalation in bronchial and systemic inflammatory markers

MFS Bond Fund Class R1 MFS Bond Fund Class R3 Mesirow Financial Enhanced Core Plus Fund Institutional Class MFS Bond Fund Class R4 MFS Bond Fund Class R6 Mesirow Financial Enhanced Core Plus Fund Investor Class Madison Government Money Market Fund Class B Meridian Contrarian Fund - Class A Shares Meridian Contrarian Fund - Class C Shares Marketfield Fund Class C Meridian Contrarian Fund - Investor Class Shares BlackRock California Municipal Opportunities Fund - C M Capital Appreciation Fund Meridian Contrarian Fund - Institutional Class Shares Federated Municipal Obligations Fd Cap Shs AMG GW&K Enhanced Core Bond ESG Fund Class - N AMG GW&K Enhanced Core Bond ESG Fund Class - I BlackRock Institutional Funds MuniFund - Dollar AMG GW&K Enhanced Core Bond ESG Fund Class - Z MFS Series Trust I - MSF Value Fund Class B MFS Growth Fund Class C MFS Growth Fund Class A MFS Growth Fund Class R3 MFS Growth Fund Class I MFS Growth Fund Class R4 MFS Growth Fund Class R6 MFS Growth Fund Class R1 MFS Lifetime 2050 Fund Class C MFS Lifetime 2050 Fund Class I MFS Lifetime 2050 Fund - Class R6 MFS Lifetime 2050 Fund Class R1 MFS Lifetime 2050 Fund Class R2 MFS Lifetime 2050 Fund Class R3 MFS Lifetime 2050 Fund Class R4 MFS Lifetime 2050 Fund Class B MFS Lifetime 2050 Fund Class A MFS Government Securities Trust B MFS Government Securities Fund Class C MassMutual Select Fundamental Growth Fund Class R4 MFS Government Securities Fund Class R1 MFS Government Securities Fund Class R3 Monteagle Quality Growth Fund MFS Government Securities Fund Class R4 MFS Government Securities Class R6 MFS Government Securities Trust A Mesirow Financial High Yield Fund Institutional Shares BlackRock Total Return Fund Class C Monteagle Fixed Income Fund Mesirow Financial High Yield Fund Investor Shares MFS Muni Income Fund Class A MFS Strategic Income Fund - Class I MFS Strategic Income Fund MSVIF Core Plus Fixed Income Portfolio Class I MS Global Fixed Income Opportunities Fund - Class IR MFS Strategic Income Fund - Class R6 BMO Tax-Free Money Market Fund - Premier MFS Lifetime 2060 Fund - Class A MFS Lifetime 2060 Fund - Class B MFS Lifetime 2060 Fund - Class C MFS Lifetime 2060 Fund - Class R1 MFS Lifetime 2060 Fund - Class R2 MFS Lifetime 2060 Fund - Class I MFS Lifetime 2060 Fund - Class R6 MFS Lifetime 2060 Fund - Class R3 MFS Lifetime 2060 Fund - Class R4 MFS Lifetime 2020 Fund Class A MFS Lifetime 2020 Fund Class B MFS Lifetime 2020 Fund Class C Marketfield Fund Class I MFS Lifetime 2020 Fund Class R1 MFS Lifetime 2020 Fund Class R2 MFS Lifetime 2020 Fund Class R3 MFS Lifetime 2020 Fund Class I MFS Lifetime 2020 Fund Class R4 MFS Lifetime 2020 Fund - Class R6 MSIF Inception Portfolio Class IS BlackRock S-T Muni Fd C Test Mutual Fund 2 - BKNY Test Mutual Fund 3 - BKNY MSIF Frontier Markets Portfolio - Class I MSIF Frontier Markets Portfolio - Class L MSIF Frontier Markets Portfolio - Class A BlackRock Strategic Municipal Opportunities Fund Cl C BlackRock NJ Muni Bnd C BlackRock New York Municipal Opportunities Fund - C BlackRock National Muni C Marsico Focus Fund BNY Mellon Focused Equity Opportunities Fund Investor Shares BNY Mellon Focused Equity Opportunities Fund Class M Shares MFS Pennsylvania Municipal Bond Fund Class A BlackRock PA Muni Bnd C AMG FQ Tax-Managed U.S

Li et al., 2021), while Keap1 expression decreased in some animal and in vitro experiments (Yan et al., 2019