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SAM is the primary methyl donor, which is a fancy way of saying its a delivery truck that drops off little tags (methyl groups) throughout the cell

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312 Avoiding long, uninterrupted, seated immobility while using a computer as well as wearing non-restrictive clothing and using comfortable sitting positions and ergonomically-designed work stations may help mitigate computer-related thrombosis risk

Prioritize protein (0.7 to 1.0 grams per pound of target body weight), eat frequent small meals rather than large infrequent ones, limit high-fat foods during dose increases to reduce nausea, stay hydrated, and avoid alcohol (which worsens both GI side effects and calorie intake)