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Clinical remission (measured by Simple Clinical Colitis Activity Index- SCCAI 2) was achieved by 53.8% of the curcumin group compared to none in the placebo group, and clinical response (3 point reduction in SCCAI) occurred in 65.3% of the curcumin group versus 12.5% in the placebo group

Somatostatin (SST) mRNA expression in the hypothalamus was markedly increased in the treatment group, whereas SST receptor (SSTR)-2 mRNA expression in the pituitary gland was decreased