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5.2.3 The comprehensive influences of exercise Studies have demonstrated that regular aerobic exercise has a obvious positive regulatory influence on the HPA axis in PTSD patients, this influence restores cortisol levels and lowers stress responses, promoting PTSD patients emotional and cognitive functions ( Further research has displayed that exercise not only strengthens HPA axis function and regulates cortisol levels, but also lowers oxidative impairment and enhances anti-stress influences, helping PTSD patients cope with emotional and psychological problems ( Whats more, in PTSD treatment, exercise may further facilitate its therapeutic influences by regulating the immune system, promoting the secretion of neurotrophic factors (such as BDNF), and anti-inflammatory substances ( Generally, regular aerobic exercise affects the HPA axis in PTSD patients by restoring cortisol levels, reducing stress responses, and facilitating emotional and cognitive functions

doi: 10.1212/WNL.0b013e31820f2d79 116 AsanumaMNishibayashi-AsanumaSMiyazakiIKohnoMOgawaN