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doi: 10.1152/ajpendo.2000.279.3.E593 130 GrabnerGFGuttenbergerNMayerNMigglautsch-SulzerAKLembacher-FadumCFawzyNet al

NAD+ is metabolized through enzymatic cleavage, salvage pathways, and poly(ADP-ribose) polymerase (PARP) activity, with primary clearance via renal and hepatic pathways