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Mol Neurobiol (2017) 54:427191

Paroxysmal nocturnal hemoglobinuria Paroxysmal nocturnal hemoglobinuria is a rare genetic disorder in which a genetic mutation causes the body to produce abnormal red blood cells that break down too quickly

However, since most studies reported either no or only mild side effects, like nausea and vomiting that could not be attributed to the treatment itself, we consider that NAC can be used as part of standard medical care until future research establishes specific indications in various etiologies