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Studies have shown that radiation can induce lung fibroblasts to secrete high amounts of lactate, leading to acidification of the extracellular environment and subsequent activation of pro-fibrotic TGF- [204]

Su forma acetilada permite una asimilacin inmediata, asegurando que los cidos grasos lleguen a las mitocondrias de forma acelerada para ser oxidados

active erastin analog erastin-A6 erastin-B2 inactive control BJeH cells gi BJeLR cells gi SLC7A5 as the lone protein bound by active erastin-A6 in both cell types