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Teng, Y., Zhao, Z., Tasnim, F., Huang, X

Results Astrocytic DRD2 facilitates GSH synthesis via Nrf2 activation To study whether dopamine receptors on neurons or astrocytes induce GSH synthesis, we treated primary neurons and astrocytes for 24 h with the typical dopamine agonist cabergoline, which has been reported to increase brain GSH levels 19

Our transcriptome analysis also revealed that genes responsive to oxidative stress were significantly induced in the systemic leaf tissues following GSH treatment (Supplementary Data 1)

Adenovirus-mediated gene delivery: potential applications for gene and cell-based therapies in the new era of personalized medicine