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In addition, GBM has relatively few tumor infiltrating T cells, and those that do infiltrate the tumor are exhausted and dysfunctional with a limited ability to mount an effective anti-tumor immune response [31, 32]

FIGURE 3 Later in another study, Oliveira and coworkers (2025) investigated the in vitro activity of another twenty-four synthesized 1,4-dihydropyridine (1,4-DHP) against Leishmania major promastigotes and amastigotes