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In addition, these studies have reported an increased relative abundance of beneficial gut microbes and a reduced relative abundance of harmful gut microbes

Interestingly, the observations made in this study also suggest that the change in plasma GPT level likely is a more sensitive biomarker for chemically-induced liver damage, whereas the increase in plasma GOT level may better reflect the degree of mitochondrial damage in injured hepatocytes in vivo

By mimicking GHRH, CJC-1295 prompts the pituitary to secrete growth hormone in a natural, pulsatile pattern rather than flooding the body with synthetic GH

doi: 10.1038/nature12362 19 BonifacioA.MartinsM