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Symptoms associated with B12 deficiency may include: Persistent fatigue or weakness Memory impairment or confusion Nerve-related issues such as numbness or tingling Mood fluctuations or depression Pale or yellowish skin A B12 deficiency can affect anyone, but older adults are particularly vulnerable

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Then, 4.88 mL of simulated intestinal fluids containing 16 U/mL pancreatin (lot number SLCM8903, trypsin activity = 8.9 U/mg) and 3.1 mM bovine bile (lot number SLBV1780, bile salts concentration = 440 g/mol) were added