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These observations correlate with those reported by Barrat et al., showing that tamoxifen-derived metabolites (i.e., 4-hydroxy-tamoxifen and endoxifen) also promote oligodendrogenesis in an estrogen receptor-dependent manner, including non-classical ERs (Table 1)

Glutathione is a compound naturally produced by the body, made from three amino acids, and plays a central role in neutralizing free radicals and supporting the livers natural detoxification process

Additionally, phospholipids are metabolized by enzymes such as N -acyltransferase (NAT), diacylglycerol lipase (DAGL), and N -acylphosphatidylethanolamine phospholipase D (NAPE-PLD) into endocannabinoids 94

Transferrin non-viral gene therapy for treatment of retinal degeneration