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Best Practice & Research Clinical Endocrinology & Metabolism, 31 (1), 91-111

Inflammatory Bowel Disease Models Research using animal models of IBD (both Crohn's-like and ulcerative colitis-like conditions) has shown BPC-157 [12]: Reduces intestinal inflammation Accelerates mucosal healing Preserves intestinal barrier function Decreases inflammatory cytokine production Prevents fistula formation in some models Intestinal Anastomosis Healing Surgical studies demonstrated that BPC-157 significantly improves the healing of intestinal anastomoses (surgical connections), potentially reducing complications like leakage and stricture formation [13]

Yes, constipation can absolutely cause back pain

Oncogene 30 , 32343247 (2011)