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An altered ratio of membrane/cytoplasm to nuclear AT 1 R expression has already been observed in patients with a neuropathological diagnosis of PD who had not yet developed clinical manifestations or significant dopaminergic neurodegeneration (267)

In summary, this study uncovered a novel role of SLC27A5 in sorafenib resistance

On the other hand, Crohn's disease is a chronic inflammatory disorder affecting the gastrointestinal tract, characterized by lesions that can appear anywhere from the mouth to the anus and can lead to extraintestinal complications [8]

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