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These definitive findings underscore L-carnitine's vital, irreplaceable role in supporting heart muscle energy, which is a critical consideration for patients desperately trying to manage the severe cardiovascular symptoms of dysautonomia and POTS

In sepsis, the uptake of FFA by cells increases, but its oxidation by mitochondria is impaired, leading to lipotoxicity

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111 Interestingly, a specific subtype of FOXA1 mutation with increased DNA affinity and chromatin-binding pattern is enriched in metastatic tumours and causes invasive phenotypes in tissue culture assays, possibly via a Wnt-dependent mechanism