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These studies have correlated symptom burden with significantly increased oxidative stress (Hyman 2010)

Further research indicates that NACorea specific 11-residue segment (68-GAVVTGVTAVA-78) within the NAC regionconstitutes the principal factor driving -synuclein aggregation and toxicity 34

In addition to CD19, other antigens such as CD20 and CD22 have also been explored as targets for CAR T-cell therapy in SLE and other autoimmune diseases