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Moreover, correlation analysis was performed between identified differential ACs and serum ALT (Table 1), demonstrating that increased ACs are significantly and positively correlated to the severity of abnormal liver function ( p 0.05, Figure 7 A), which may explain the absence of changes in SCACs and MCACs in the ALF group compared with the NLF group
Despite the limited diagnostic capabilities of many current biomarkers, future research should aim to enhance diagnostic accuracy and efficiency through the integration of technologies such as artificial intelligence and machine learning
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