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By reducing lipid hydroperoxides in the presence of ferrous iron, Fer-1 prevents lipid membrane damage and exerts potent anti-ferroptotic effects ( T4, a G-actin sequestering peptide, plays a pivotal role in regulating actin polymerization and is implicated in a wide range of critical biological processes, including cell migration, wound healing, and inflammation ( GB, a terpenoid compound derived from Ginkgo biloba leaves and root bark, is one of the key bioactive constituents known for its therapeutic properties ( Lip-1, a spiroquinoxaline derivative, exhibits potent and selective inhibitory effects on iron-dependent lipid peroxidation pathways, making it a promising candidate for targeting ferroptosis

Infusing Vitamin C intravenously allows reaching plasma concentrations that would be impossible through oral intake (due to gut absorption limits)

These problems can be eliminated by supplementing with plant protein, and replacing fish protein can improve subacute pathological gut problems

For all experiments involving stable isotope tracers, including 1- 13 C-glucose, 1,2- 13 C-glucose, U- 13 C-glucose and 3- 2 H-glucose (all from Cambridge Isotope), isotopically labelled glucose was substituted for unlabelled glucose at the same concentration in RPMI culture medium