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5 and 9 of Jung, J., et al., Nicotinamide metabolism regulates glioblastoma stem cell maintenance JCI Insight, 2:1-23 (2017)

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Growth hormone therapy can induce insulin resistance, elevate fasting glucose, worsen glycemic control in diabetics or pre-diabetics, increase risk of developing type 2 diabetes with long-term use, and require medication adjustments for individuals with existing diabetes