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Gawne PJ, Ferreira M, Papaluca M, Grimm J, Decuzzi P

Cell Death Dis (2022) 13:573

These two pathways have overlapping functions, but insulin is mainly involved in the regulation of metabolism, and the Growth Hormone/IGF-1 pathway plays an important role in the processes of growth, development and possibly life expectancy

then superoxide anions can react with reducing substances or biological macromolecules, for example superoxide dismutase (SOD) to produce H 2 O 2 [21]