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A postmortem MRI and histopathology study

Loss of those selenoproteins in Se deficiency allows more viral copies to be generated per unit time giving more opportunities for the emergence of mutations that are the basis for evolutionary selection of more virulent strains (Reference Moya, Elena and Bracho15,Reference Domingo16,Reference Corey, Beyrer and Cohen17)

However, Hebbian-type plasticity rules introduce an intrinsic positive feedback on synaptic weight changes, making synapses prone to runaway potentiation or depression and eventual saturation, and making neuronal activity prone to runaway activation or complete silencing

On activation CD4+ T cells differentiate into Th1 and Th17 subtypes, releasing cytokines like IL-17 and IFN- , these cytokines further stimulate neutrophils and macrophages, resulting in the onset of intestinal inflammation (63)