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Therefore, both papers demonstrated that it is possible to derive disease-free patient-specific iPSCs lines from patients with a low burden of a mosaic genetic abnormality

CYP450 oxidation activity followed a similar pattern as GSH initial concentration and production rate, with the normalized number of zonal necrosed cells increasing from 2.2 times at 20% zonation to 13.2 times at 80% zonation

Siler 3 , (1)Merck and Co Inc, (2)Cardiometabolic Diseases, Merck & Co., Inc., South San Francisco, CA, (3)Simulations Plus Background: Non-alcoholic steatohepatitis (NASH) is a metabolic disease that is characterized by increased liver fat, inflammation, and fibrosis

PMID 12195242