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This review analyzed the effects of caffeine, mainly in a scenario of neuroinflammation in animal models of anxiety and depression

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KEGG pathway analysis revealed that upregulated DEGs were enriched in Metabolic pathways, Alanine, aspartate and glutamate metabolism, Chemical carcinogenesis-DNA adducts, Steroid hormone biosynthesis, Biosynthesis of amino acids, Retinol metabolism and Metabolism of xenobiotics by cytochrome P450 (Fig