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Complications of Untreated B12 Deficiency Permanent nerve damage Cognitive problems like dementia Heart disease Infertility Depression and anxiety Worsening of autoimmune conditions Preventing Vitamin B12 Deficiency Eat a balanced diet rich in animal products or fortified foods

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Holotranscobalamin is the biologically active form bound to transcobalamin II, accounting for 20% to 25% of the total measured vitamin B12