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Cloudiness, difficulty dissolving, or visible particles suggest degradation

However, other studies found increased CSF permeability and BBB disruption in a subset of patients infected with SARS-CoV-2 with elevated Q-albumin ratios that correlated with markers of inflammation 64

This interacts with the HPA axis your body's central stress-response system in a straightforward way: when you're physically exhausted and neurologically compromised, cortisol stays elevated longer, recovery from stressful events takes more time, and the subjective experience of stress intensifies