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Papaharalambus CA, Griendling KK

A synergistic interaction is defined as a combination of stressors that results in a greater effect than the cumulative expected effect from independent exposure 34

Reference ranges vary between laboratories, so results should be interpreted according to local thresholds

Increased activity of these phase II detoxification enzymes enhances the bodys ability to manage oxidative stress and inflammatory mediators that contribute to metabolic syndrome (Ngo and Duennwald, 2022)