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Its a peptide too large and too polar to cross the gut, and it gets destroyed by enzymes before itd get the chance

You should also meet with the medical team if youre overweight and have obesity-related, chronic health conditions like type 2 diabetes, hypertension (high blood pressure), or high cholesterol

Its also important to follow up with your healthcare provider for regular blood tests to ensure that your B12 levels remain stable

Another factor that can increase the risk of a B12 deficiency is a lack of a diverse diet, says Emily Peron, associate professor in the department of pharmacotherapy and outcomes science at Virginia Commonwealth University