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With no head-to-head study, comparing the two requires stitching together trials that differ in population, comparator, endpoint, and duration a chain with several weak links

The combination of GSTM1 active and GSTT1 active genotype decreased the risk of ASD (OR = 0.126, 95%CI: 0.0290.547, p = 0.006), as well as combination of GSTT1 active and GSTP1 llelle (OR = 0.170, 95%CI: 0.0290.992, p = 0.049)