l glutathione reduced manufacturer G22010-100.0 These capsules are easy to swallow and can readily be incorporated into daily wellness routines L-Glutathione (Reduced), 500 mg, 50

Abbreviations GCLC: Glutamate cysteine ligase catalytic subunit GCLM: Glutamate cysteine ligase modifier subunit GSH: Reduced glutathione GSSG: Oxidized glutathione ROS: Reactive oxygen species C1q: Complement component 1q C3: Complement component 3 GSDMD: Gasdermin D GSDME: Gasdermin E DAM: Disease associated microglia DAA: Disease associated astrocyte Iba1: Ionized calcium-binding adapter molecule 1 GFAP: Glial fibrillary acidic protein NeuN: Neuronal nuclei HO1: Hemeoxygenase 1 CCL: CC Chemokine ligand CXCL: C-X-C motif ligand AD: Alzheimers disease App: Amyloid precursor protein A: Amyloid beta App : NL-G-F App knockin mouse NL-G-F References Guo, C., Sun, L., Chen, X

Gastroenterology 141(4):12201230 Ji Y et al (2019) Gut microbiota-derived components and metabolites in the progression of non-alcoholic fatty liver disease (NAFLD)

One meta-analysis that included findings from 22 randomized controlled trials with a total of 3,604 participants found treatment with folic acid not only lowered homocysteine levels but also improved cognitive function in those with mild cognitive impairment

62 FuruhashiS.SugitaH.TakamoriH.HorinoK.NakaharaO.OkabeH.et al (2012)