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Autophagy, an intracellular process that catabolizes intracellular components through lysosomal degradation, plays a crucial role in the host defense against intracellular pathogens like M.tb [57] (Fig

Its effects require intact amylin receptor signaling, as demonstrated in receptor knockout models where weight loss is abolished, and structural studies show unique conformational dynamics at these receptors compared to native amylin or other analogs

What causes the cyst to form is the accumulation or overproduction of synovial fluid