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By using genetics and in vitro proteolytic assays alongside mass spectrometry, we found that F1 and F2 are the two cleavage products of PrtP

Moreover, TSA reduced cardiac hypertrophy in SHRs by inhibiting the Cys-C/Wnt signaling pathway, decreasing protein expression of Cys-C, Wnt2, -catenin and WISP-1 (107)

APA significantly impacts human pathogenesis by influencing mRNA stability, localization and translation, thereby affecting the expression and function of crucial genes

The keloid tissues for organ culture were firstly incubated in a DMEM containing 10% FBS at 37 C for 24 h, and the medium was replaced by the DMEM containing 2% FBS, the final concentration of 25 M FOXO4-DRI was added in the medium immediately